Coming to you from Ile de Berder
I’ll let you have the fun of finding it on a Google map.
Wonderful (surprising, given the forecast) sun and an extremely limited wifi range. So I’ll keep it very short and sweet.
About mid-morning, after my own talk on vertebral development, I went to get my computer and set up in the back of a room close to a plug to take notes, instead of scribbling furiously. My battery life is down to something like 20 minutes and the ventilation fan sounds like an asthmatic mosquito. But I took some mighty fine notes that I will plug into my “lab notebook” because if I put this sort of thing on here, it would look like this
Spondylocostal dysostosis
Concerns the whole A-P axis, like a craniorachischisis. Mutations in MESP2 and DLL3. The vertebrae are in “galet” shape – flat, smoothened. Can be associated with neural tube defects (NTDs), anal imperforation and heart malformations. Not dysmorphic. Get hemi-vertebrae and short thorax, head in the shoulders. Mostly sporadic. Autosomal dominant (AD) forms are more moderate.
DLL# is on 19q31; heterozygous mutations given the same phenotype as hmz
Remember that hairy/enhancer-of-split genes repress achaete-scute-like Mash/HASH gene transcription.
and probably not make for very interesting reading for most of you. And when faced with the possibility of joining a group of people in the sunshine with a Cervoise Lancelot, well, it’s no contest between that and blogging.
Posted on Thursday, July 3rd, 2008 at 12:17 pm Categorized as:General You can leave a response, or trackback from your own site.
